COMPUTATIONAL PREDICTION OF VACCINE POTENTIAL EPITOPES AND 3-DIMENSIONAL STRUCTURE OF XAGE-1B FOR NON-SMALL CELL LUNG CANCER IMMUNOTHERAPY

Computational prediction of vaccine potential epitopes and 3-dimensional structure of XAGE-1b for non-small cell lung cancer immunotherapy

Background: XAGE-1b is shown to be overexpressed in lung adenocarcinoma and to be a strong immunogenic antigen among non-small cell lung cancer ranchy doodle (NSCLC) patients.However, 3D structure of XAGE-1b is not available and its confirmation has not been solved yet.Methods: Multiple sequence alignment was run to select the most reliable templat

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Contextualizing Western guidelines for stroke and low back pain to a developing country (Philippines): an innovative approach to putting evidence into practice efficiently

Consuelo Gonzalez-Suarez,1,2,3 Karen Grimmer-Somers,1 Janine Margarita Dizon,1 Ellena King,1 Sylvan Lorenzo,2 Carolina Valdecanas,2 Ephraim Gambito,2 Belinda Fidel2,31International Center for Allied Health Evidence, University of South Australia, Adelaide, Australia; 2Philippine Academy of Rehabilitation Medicine, Quezon City, Philippines; 3Univers

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Inertial Microfluidics Enabling Clinical Research

cath kidston forget me not Fast and accurate interrogation of complex samples containing diseased cells or pathogens is important to make informed decisions on clinical and public health issues.Inertial microfluidics has been increasingly employed for such investigations to isolate target bioparticles from liquid samples with size and/or deformabil

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Economic Evaluation of Nirmatrelvir/Ritonavir Among Adults Against Hospitalization During the Omicron Dominated Period in Malaysia: A Real-World Evidence Perspective

Abstract Background and objectives Nirmatrelvir/ritonavir was administered orally to manage mild to moderate symptoms of COVID-19 in adult patients.The objectives of this study were to (i) evaluate the cost-effectiveness of prescribing nirmatrelvir/ritonavir within 5 tech lighting tellium days of a COVID-19 illness in order to avert hospitalization

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